Benzyl-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 702701-70-0

Molecular Weight: 318.39

Formula: C14H22O6S

Chemical Name: 2-{2-[2-(benzyloxy)ethoxy]ethoxy}ethyl methanesulfonate

Smiles: CS(=O)(=O)OCCOCCOCCOCC1C=CC=CC=1

InChiKey: MEUSATKDKDWEPY-UHFFFAOYSA-N

InChi: InChI=1S/C14H22O6S/c1-21(15,16)20-12-11-18-8-7-17-9-10-19-13-14-5-3-2-4-6-14/h2-6H,7-13H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.