S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosaccharomyces pombe and Mycobacterium tuberculosis lumazine synthases, respectively.

Product information

CAS Number: 331726-35-3

Molecular Weight: 321.29

Formula: C14H15N3O6

Chemical Name: 6-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-5-nitro-1,3-diazinane-2,4-dione

Smiles: COC1=CC=C(C=C1OC)/C=C/C1NC(=O)NC(=O)C1[N+]([O-])=O

InChiKey: WLNYQKNCYDJGRA-HWKANZROSA-N

InChi: InChI=1S/C14H15N3O6/c1-22-10-6-4-8(7-11(10)23-2)3-5-9-12(17(20)21)13(18)16-14(19)15-9/h3-7,9,12H,1-2H3,(H2,15,16,18,19)/b5-3+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 31.25 mg/mL (97.88 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

S.pombe lumazine synthase-IN-1 (Compound 21) is a class II compound with OCH3 groups displays slightly better potencies than its counterparts with OH groups.

Products are for research use only. Not for human use.