CD66a/e Polyclonal Antibody

Catalogue Numbers: BS67002-50, BS67002-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P13688; P06731

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner (By similarity).Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesis (PubMed:18424730, PubMed:23696226, PubMed:25363763).Its coinhibitory receptor function is phosphorylation- and PTPN6 -dependent, which in turn, suppress signal transduction of associated receptors by dephosphorylation of their downstream effectors. Plays a role in immune response, of T cells, natural killer (NK) and neutrophils (PubMed:18424730, PubMed:23696226).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of CD66a/e protein.

Extra Notes: Western blot analysis of CD66a/e expression in HUT78 (A), HCT116 (B) whole cell lysates.

Bioworld Molecular Weight: ~ 180 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: CEACAM1; BGP; BGP1; Carcinoembryonic antigen-related cell adhesion molecule 1; Biliary glycoprotein 1; BGP-1; CD66a; CEACAM5; CEA; Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD66a/e. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified