Polyethylene glycol 12-hydroxystearate, a Macrogol 15 hydroxy stearate, is a permeability enhancer.

Product information

CAS Number: 61909-81-7

Molecular Weight: 344.53

Formula: C20H40O4

Chemical Name: 2-hydroxyethyl 12-hydroxyoctadecanoate

Smiles: CCCCCCC(O)CCCCCCCCCCC(=O)OCCO

InChiKey: JVKUCNQGESRUCL-UHFFFAOYSA-N

InChi: InChI=1S/C20H40O4/c1-2-3-4-11-14-19(22)15-12-9-7-5-6-8-10-13-16-20(23)24-18-17-21/h19,21-22H,2-18H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Polyethylene glycol 12-hydroxystearate is used to increase the aqueous solubility of Biopharmaceutical Classification System (BCS) Class 2 and 4 lipophilic molecules. Polyethylene glycol 12-hydroxystearate has shown an enhancement in permeability of medium sized biological drugs across epithelia.

Products are for research use only. Not for human use.