Histamine H1 Receptor (K179) Polyclonal Antibody

Catalogue Numbers: BS2733-50, BS2733-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P35367

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. The effects of histamine are mediated by a family of G protein-coupled receptors, the Histamine H1, H2, H3 and H4 Receptors. The gene encoding the human Histamine H1 Receptor maps to chromosome 3p25 and is expressed in highest abundance in placenta, with lower levels in lung, skeletal muscle, kidney and brain. The murine Histamine H2 Receptor gene maps to chromosome 13 and is highly expressed in stomach with moderate expression in brain and heart. The gene encoding the human Histamine H3 Receptor is located on chromosome 20 and is expressed as six alternative splice variants in thalamus.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Histamine H1 Receptor (K179) polyclonal antibody detects endogenous levels of Histamine H1 Receptor protein.

Extra Notes: Western blot (WB) analysis of Histamine H1 Receptor (K179) polyclonal antibody at 1:500 dilution
Lane1:HEK293T whole cell lysate(40ug)
Lane2:Hela whole cell lysate(40ug)
Lane3:The Testis tissue lysate of Rat(40ug)

Bioworld Molecular Weight: ~ 55,70 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Histamine H1 receptor; H1R; HH1R; HRH1

Immunogen: Synthetic peptide, corresponding to Human Histamine H1 Receptor.

Conjugate: Unconjugated

Modification: Unmodified