Direct Blue 1 (Chicago Sky Blue 6B) is a counterstain for background autofluorescence in immunofluorescence histochemistry. Direct Blue 1, structurally related to glutamate, is a potent and competitive VGLUT inhibitor without affecting plasma membrane transporters. Direct Blue 1 is the first small molecule PrP ligand capable of inhibiting Aβ binding.

Product information

CAS Number: 2610-05-1

Molecular Weight: 992.80

Formula: C34H24N6Na4O16S4

Chemical Name: tetrasodium 4-amino-6-(2-{4'-[2-(8-amino-1-hydroxy-5,7-disulfonatonaphthalen-2-yl)diazen-1-yl]-3,3'-dimethoxy-[1,1'-biphenyl]-4-yl}diazen-1-yl)-5-hydroxynaphthalene-1,3-disulfonate

Smiles: [Na+].[Na+].[Na+].[Na+].COC1=CC(=CC=C1N=NC1C=CC2=C(C=1O)C(N)=C(C=C2S([O-])(=O)=O)S([O-])(=O)=O)C1=CC(OC)=C(C=C1)N=NC1C=CC2=C(C=1O)C(N)=C(C=C2S([O-])(=O)=O)S([O-])(=O)=O

InChiKey: BPHHNXJPFPEJOF-GPTZEZBUSA-J

InChi: InChI=1S/C34H28N6O16S4.4Na/c1-55-23-11-15(3-7-19(23)37-39-21-9-5-17-25(57(43,44)45)13-27(59(49,50)51)31(35)29(17)33(21)41)16-4-8-20(24(12-16)56-2)38-40-22-10-6-18-26(58(46,47)48)14-28(60(52,53)54)32(36)30(18)34(22)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-37+,40-38+;;;;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 125 mg/mL (125.91 mM; Need ultrasonic). H2O : 2.08 mg/mL (2.10 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.