CH2COOH-PEG9-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2250056-46-1

Molecular Weight: 530.56

Formula: C22H42O14

Chemical Name: 3,6,9,12,15,18,21,24,27,30-decaoxadotriacontanedioic acid

Smiles: OC(=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(O)=O

InChiKey: GRKZSKXPALQEJJ-UHFFFAOYSA-N

InChi: InChI=1S/C22H42O14/c23-21(24)19-35-17-15-33-13-11-31-9-7-29-5-3-27-1-2-28-4-6-30-8-10-32-12-14-34-16-18-36-20-22(25)26/h1-20H2,(H,23,24)(H,25,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.