4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes.

Product information

CAS Number: 14348-38-0

Molecular Weight: 217.02

Formula: C7H5BrO3

Chemical Name: 4-bromo-3-hydroxybenzoic acid

Smiles: OC1=CC(=CC=C1Br)C(O)=O

InChiKey: PAJSESFUWIYFNF-UHFFFAOYSA-N

InChi: InChI=1S/C7H5BrO3/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,9H,(H,10,11)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

IC50: 1 mM (Rat fetal histidine decarboxylase (HDC)), 1 mM (Ratgastric HDC), 1 mM (Hog kidney aromatic-L-amino acid decarboxylase), 1 mM (Rat gastric mucosa aromatic-L-amino acid decarboxylase)

Products are for research use only. Not for human use.