Bis-NH2-C1-PEG3 (PROTAC Linker 24) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 4246-51-9

Molecular Weight: 220.31

Formula: C10H24N2O3

Chemical Name: 3-{2-[2-(3-aminopropoxy)ethoxy]ethoxy}propan-1-amine

Smiles: NCCCOCCOCCOCCCN

InChiKey: JCEZOHLWDIONSP-UHFFFAOYSA-N

InChi: InChI=1S/C10H24N2O3/c11-3-1-5-13-7-9-15-10-8-14-6-2-4-12/h1-12H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.